It can also cause a common and sometimes serious respiratory germ The risk of developing asthma if it is encountered early In life, new research suggests this month. The study found that children were more likely to do so They develop asthma if they get a respiratory syncytial virus (RSV) infection before the age of 1. The results may highlight another benefit Effective vaccines and treatments for RSV that are expected to reach the public soon.
RSV is one of the most ubiquitous respiratory germs, with most people is expected Infection at the age of two. The infection usually causes mild cold symptoms, such as a runny nose, coughing, and sneezing. But they carry a greater risk of causing serious, even life-threatening disease, in the very young and old. According to the Centers for Disease Control and PreventionRSV receives tens of thousands of Americans over the age of 65 and under the age of 5 each year.
For many years now, studies have been Proposal Severe RSV infection in childhood can increase people’s risk of developing asthma and allergies. But there’s still a lot we don’t understand about this association, including the exact risk factors that may make children more likely to develop asthma after infection with RSV. This new study, conducted by researchers in Tennessee, was Designed to discover some of these factors.
The research is called Infant Susceptibility to Pneumonia and Asthma After Exposure to RSV, or the INSPIRE study. The researchers proactively followed about 1,700 healthy children born in the state between 2012 and 2013 for up to five years. Along the way, they tracked when and if children were exposed to RSV and whether they were diagnosed with asthma at the age of five.
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Overall, nearly half of all children were infected with RSV in their first year of life, and these children were more likely to develop asthma by the time they reached the age of five.. Specifically, children who were infected with RSV in childhood had a 26% higher risk of developing asthma than those who did not develop it early on. The team’s findings were published earlier this month in scalpel.
her previous research Proposal There is a shared genetic component that underlies the link between acute respiratory syncytial virus and asthma. In other words, the same genetic differences that make a child more susceptible to severe RSV appear to make them more likely to develop asthma. These new findings do not invalidate this earlier work, however It will probably add a new crease. As is often the case in medicine, it may be environment and genetics that influence a child’s risk of developing asthma after infection with RSV.
“We focused on the first year of life because we believe the first year is a very important period for lung and immune development,” said study author Christian Rosas-Salazar, MD, a pediatrician at Vanderbilt University Medical Center. a permit from the University. “We think that when a child gets infected with RSV in the first year of life, when the lungs and immune system are still developing, it can lead to some abnormalities that can cause asthma later on.”
While the early years of the pandemic saw a decline in many common infections, these germs — including RSV — have since returned in full force. The impact of RSV on the very young and the elderly This has long made it an attractive target for vaccination and other treatments. aAfter decades of failure, we are finally on the cusp of several effective vaccines the elderly , new bornand even expectant mothers who can pass their immunity on to their children.
It’s unIt is not known whether any of these vaccines can provide long-term protection yet, but they should significantly reduce the risk of serious illness before the RSV season (usually winter), like the annual flu vaccine. Given the team’s findings here, it’s also worth discovering iCan Childhood RSV Vaccines Prevent RSV-Related Asthma, Study Aauthors says.
“We hope that the results of this study will stimulate long-term follow-up of respiratory outcomes common among children in ongoing clinical trials of RSV prevention products, including vaccines and monoclonal antibodies that can reduce the severity of infection,” said Rosas-Salazar.